生物活性 | |||
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描述 | Cligosiban (PF-3274167), a non-peptide oxytocin receptor antagonist with high oral bioavailability and good brain penetration, exhibits high affinity (Ki=9.5 nM) and excellent selectivity against vasopressin receptors, particularly V1b and V1a subtypes. Cligosiban inhibits ejaculatory physiology in rodents[1][2]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.38mL 0.48mL 0.24mL |
11.91mL 2.38mL 1.19mL |
23.82mL 4.76mL 2.38mL |
参考文献 |
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