产品说明书
Ergosterol peroxide
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同义名 : | Ergosterol Endoperoxide;NSC 31324 |
| CAS号 : | 2061-64-5 | |
| 货号 : | A460931 | |
| 分子式 : | C28H44O3 | |
| 纯度 : | 99+% | |
| 分子量 : | 428.647 | |
| MDL号 : | MFCD01746240 | |
| 存储条件： |
粉末 Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 10 mg/mL(23.33 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ergosterol peroxide, a natural product isolated and purified from the herbs of Isodon eriocalyx with antioxidant activity and antibiotic activity against mycobacterium tuberculosis, exerts antitumor activity in multiple myeloma U266 cells partly with antiangiogenic activity targeting JAK2/STAT3 signaling pathway as a potent cancer preventive agent for treatment of multiple myeloma cells, appears to suppress cell growth and STAT1 mediated inflammatory responses by altering the redox state in HT29 cells, suppresses LPS-induced inflammatory responses through inhibition of NF-κB and C/EBPβ transcriptional activity, and phosphorylation of MAPKs. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.33mL 0.47mL 0.23mL |
11.66mL 2.33mL 1.17mL |
23.33mL 4.67mL 2.33mL |
| 参考文献 |
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