生物活性 | |||
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靶点 |
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描述 | Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4[1]. In vitro, Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells[2]. Otherwise, Butein also sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a[3]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.67mL 0.73mL 0.37mL |
18.37mL 3.67mL 1.84mL |
36.73mL 7.35mL 3.67mL |
参考文献 |
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