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Glyoxalase I inhibitor

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Chemical Structure| 221174-33-0 同义名 : -
CAS号 : 221174-33-0
货号 : A448974
分子式 : C21H30BrClN4O8S
纯度 : 98+%
分子量 : 613.907
MDL号 : MFCD20270724
存储条件：

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(57.01 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.63mL

0.33mL

0.16mL

8.14mL

1.63mL

0.81mL

16.29mL

3.26mL

1.63mL
参考文献

[1]Hollenbach M, Thonig A, et al. Expression of glyoxalase-I is reduced in cirrhotic livers: A possible mechanism in the development of cirrhosis. PLoS One. 2017 Feb 23;12(2):e0171260.

[2]Al-Balas QA, Hassan MA, et al. Novel glyoxalase-I inhibitors possessing a "zinc-binding feature" as potential anticancer agents. Drug Des Devel Ther. 2016 Aug 17;10:2623-9.