(S)-Dolaphenine HCl

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Chemical Structure| 135383-60-7 同义名 : (S)-Dolaphenine hydrochloride
CAS号 : 135383-60-7
货号 : A442497
分子式 : C11H13ClN2S
纯度 : 99%+
分子量 : 240.752
MDL号 : MFCD11841121
存储条件：

Pure form Inert atmosphere,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(207.68 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(207.68 mM)
动物实验配方：
生物活性
描述 (S)-Dolaphenine hydrochloride is a component of Dolastatin 10, an antineoplastic agent known for its ability to inhibit tubulin polymerization, which disrupts cell division and is used in cancer treatment[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.15mL

0.83mL

0.42mL

20.77mL

4.15mL

2.08mL

41.54mL

8.31mL

4.15mL
参考文献

[1]Zhou W , et al. A practical approach to asymmetric synthesis of dolastatin 10. Org Biomol Chem. 2017;15(29):6119-6131.