Esculin
产品说明书
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同义名 : | 马栗树皮甙 ;Aesculin |
| CAS号 : | 531-75-9 | |
| 货号 : | A441939 | |
| 分子式 : | C15H16O9 | |
| 纯度 : | 99% | |
| 分子量 : | 340.282 | |
| MDL号 : | MFCD00006879 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(308.57 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Esculin is a derivative of coumarin, which is also an active ingredient of ash bark, and has antibacterial, anti-inflammatory, anti-allergy and skin protective effects [3]. Esculin significantly reduced the pathological symptoms of acute liver injury, as well as serum AST (Aspartate aminotransferase) and ALT (Alamine aminotransferase) levels. Furthermore, LPS/D-Gal-induced liver tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) production were attenuated by esculin[5]. Esculin (5, 10 or 20 mg/kg ) may ameliorate cognitive impairment in experimental DN (diabetic nephropathy), and exert anti-oxidative stress and anti-inflammatory effects[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.94mL 0.59mL 0.29mL |
14.69mL 2.94mL 1.47mL |
29.39mL 5.88mL 2.94mL |
| 参考文献 |
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