产品说明书

Palmatine

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Chemical Structure| 3486-67-7 同义名 : 巴马汀 ;Berbericinine;Burasaine
CAS号 : 3486-67-7
货号 : A441382
分子式 : C21H22NO4
纯度 : 98%
分子量 : 352.404
MDL号 : MFCD00221758
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
靶点

  • AChE

    AChE, IC50:0.51 μM
描述 Palmatine, a natural product isolated and purified from the rhizomes of Coptis chinensis Franch., is an inhibitor of dopamine generation. Palmatine could potentially be developed for the treatment of flavivirus infections.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.84mL

0.57mL

0.28mL

14.19mL

2.84mL

1.42mL

28.38mL

5.68mL

2.84mL
参考文献

[1]Vrba J, Havlikova M, et al. Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes. Toxicol In Vitro. 2014 Jun;28(4):693-9.

[2]Dhingra D, Bhankher A. Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress. Pharmacol Rep. 2014 Feb;66(1):1-9.