产品说明书

(Z)-Thiothixene

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Chemical Structure| 3313-26-6 同义名 : -
CAS号 : 3313-26-6
货号 : A439269
分子式 : C23H29N3O2S2
纯度 : 99%+
分子量 : 443.625
MDL号 : MFCD00079574
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 9 mg/mL(20.29 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 (Z)-Thiothixene promotes cell survival and/or plasticity, and/or inhibits cell death, especially when cells, including neuronal cells, are exposed to toxic substances[1].(Z)-Thiothixene is a Z (cis) isomer of thiothixene and is also a synthetic precursor and degradation agent[2].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01231074 Obesity Weigh... 展开 >>t Gain Psychotropic Induced Weight Gain 收起 << Phase 1 Unknown May 2011 United States, Ohio ... 展开 >> Nationwide Children's Hospital Recruiting Columbus, Ohio, United States, 43205 Contact: Ihuoma Eneli, MD, MS    614-722-4089    ihuoma.eneli@nationwidechildrens.org    Contact: Mary Ann Murphy, MD, PhD    614-722-2291    maryann.murphy@nationwidechildrens.org 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.25mL

0.45mL

0.23mL

11.27mL

2.25mL

1.13mL

22.54mL

4.51mL

2.25mL
参考文献

[1]Illana Gozes, et al. Novel compounds and methods for inhibiting cell death. US 20150141345 A1.

[2]Severin G. Comprehensive high-performance liquid chromatographic methodology for the determination of thiothixene in bulk drug, finished product, and dissolution testing samples. J Pharm Sci. 1987 Mar;76(3):231-4.