产品说明书

10-Deacetyl-7-xylosyl paclitaxel

Print
Chemical Structure| 90332-63-1 同义名 : 10-Deacetyl-7-xylosyltaxol;10-Deacetylpaclitaxel 7-Xyloside;7-xylosyl-10-deacetylpaclitaxel;10-Deacetyltaxol 7-Xyloside
CAS号 : 90332-63-1
货号 : A439063
分子式 : C50H57NO17
纯度 : 98%
分子量 : 943.984
MDL号 : MFCD09039072
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(37.08 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 7-Xylosyl-10-deacetyltaxol is a paclitaxel derivative with improved pharmacological features and higher water solubility.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.06mL

0.21mL

0.11mL

5.30mL

1.06mL

0.53mL

10.59mL

2.12mL

1.06mL
参考文献

[1]Dou TY, Luan HW, et al. Functional and structural properties of a novel cellulosome-like multienzyme complex: efficient glycoside hydrolysis of water-insoluble 7-xylosyl-10-deacetylpaclitaxel. Sci Rep. 2015 Sep 8;5:13768.

[2]Jiang S, Zu Y, et al. Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int J Oncol. 2008 Jul;33(1):103-11.