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1-Methyl-2-nonyl-4(1H)-quinolone

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Chemical Structure| 68353-24-2 同义名 : -
CAS号 : 68353-24-2
货号 : A431254
分子式 : C19H27NO
纯度 : 98+%
分子量 : 285.43
MDL号 : -
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 1-Methyl-2-nonylquinolin-4(1H)-one, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth. with anti-inflammatory activity. It exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 mM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.50mL

0.70mL

0.35mL

17.52mL

3.50mL

1.75mL

35.03mL

7.01mL

3.50mL

参考文献

[1]Adams M, Kunert O, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8.