Ginsenoside F2

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Chemical Structure| 62025-49-4 同义名 : -
CAS号 : 62025-49-4
货号 : A420467
分子式 : C42H72O13
纯度 : 99%
分子量 : 785.01
MDL号 : MFCD06410948
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(63.69 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Ginsenoside F2, a natural product isolated and purified from the root of Panax ginseng C. A. Mey. with antiproliferative activity against breast cancer stem cells (CSCs), decreases the expression of TGF-β2 and SCAP proteins which involved in apoptosis, and increases the expression of β-catenin and Lef-1 which as a major factor related to the development and growth of hair follicle and the decrease in DKK-1 when entering catagen.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.27mL

0.25mL

0.13mL

6.37mL

1.27mL

0.64mL

12.74mL

2.55mL

1.27mL
参考文献

[1]Siraj FM, SathishKumar N, et al. Ginsenoside F2 possesses anti-obesity activity via binding with PPARγ and inhibiting adipocyte differentiation in the 3T3-L1 cell line. J Enzyme Inhib Med Chem. 2015 Feb;30(1):9-14.

[2]Shin HS, Park SY, et al. Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. Biol Pharm Bull. 2014;37(5):755-63.