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N-[(4-Aminophenyl)methyl]adenosine

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Chemical Structure| 95523-13-0 同义名 : -
CAS号 : 95523-13-0
货号 : A403075
分子式 : C17H20N6O4
纯度 : 98%
分子量 : 372.378
MDL号 : MFCD00083216
存储条件：

粉末 Keep in dark place,Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 9 mg/mL(24.17 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor, with Ki of 29 nM for rat ecto-5′-nucleotidase.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.43mL

2.69mL

1.34mL

26.85mL

5.37mL

2.69mL
参考文献

[1]Bhattarai S, Freundlieb M, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63.

[2]Chen JB, Liu EM, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-400.