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Picfeltarraenin IA

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Chemical Structure| 97230-47-2 同义名 : -
CAS号 : 97230-47-2
货号 : A401291
分子式 : C41H62O13
纯度 : 98%
分子量 : 762.923
MDL号 : N/A
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(137.63 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Picfeltarraenin IA, a natural product isolated and purified from the herbs of Picria felterrae Lour., is a stronger AChE inhibitor than the known AChE inhibitor Tacrine, a potential PI3K and epidermal growth factor receptor (EGFR ) inhibitor with anti-inflammatory activity, and acts as an inhibitor on both the classical and alternative pathways of the complement system.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.31mL

0.26mL

0.13mL

6.55mL

1.31mL

0.66mL

13.11mL

2.62mL

1.31mL
参考文献

[1]Wen L, Wei Q, et al. Bioassay- and liquid chromatography/mass spectrometry-guided acetylcholinesterase inhibitors from Picriafel-terrae. Pharmacogn Mag. 2013 Oct;9(Suppl 1):S25-31.

[2]Zou JM, Wang LS, et al. A new cucurbitacin from Picria fel-terrae. J Asian Nat Prod Res. 2006 Jun;8(4):367-71.