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Chrysosplenetin

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Chemical Structure| 603-56-5 同义名 : Chrysosplenol B;Polycladin;Quercetagetin 3,6,7,3′-tetramethyl ether;Jaceidin 7-O-methyl ether;Chrysosplenetin (6CI);Chrysosplenetin B;EMD 20940;Chrysosptertin B
CAS号 : 603-56-5
货号 : A397520
分子式 : C19H18O8
纯度 : 98%
分子量 : 374.341
MDL号 : MFCD01083081
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(280.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.67mL

0.53mL

0.27mL

13.36mL

2.67mL

1.34mL

26.71mL

5.34mL

2.67mL
参考文献

[1]Chen J, Ji HY, et al. [Determination of chrysosplenetin, metabolic inhibitor of artemisinin, in rat plasma by UPLC-ms/MS and study on its pharmacokinetics] . Zhongguo Zhong Yao Za Zhi. 2013 Oct;38(19):3363-7.

[2]Zhu QC, Wang Y, et al. Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin. Eur J Pharm Sci. 2011 Oct 9;44(3):392-8.