产品说明书

Goniothalenol

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Chemical Structure| 65408-91-5 同义名 : -
CAS号 : 65408-91-5
货号 : A396931
分子式 : C13H12O4
纯度 : 98+%
分子量 : 232.23
MDL号 : -
存储条件：

粉末 2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Altholactone, a natural product isolated and purified from the herbs of Goniothalamus malayanus, can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladder cancer, colon carcinoma cells and may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.31mL

0.86mL

0.43mL

21.53mL

4.31mL

2.15mL

43.06mL

8.61mL

4.31mL
参考文献

[1]Zhao B, Li X. Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression. Oncol Rep. 2014 Jun;31(6):2769-75.

[2]Uthaisang-Tanechpongtamb W, Sriyabhaya P, Wilairat P. Role of altholactone in inducing type II apoptosis signalling pathway and expression of cancer-related genes in cervical carcinoma HeLa cell line. Cell Biol Int. 2013 May;37(5):471-7.