H-Cys-OH
产品说明书
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同义名 : | (R)-2-氨基-3-巯基丙酸 ;Cysteine;L-Cys;Cysteinum;FEMA No. 3263;NSC 8746;(R)-Cysteine;L-(+)-Cysteine |
| CAS号 : | 52-90-4 | |
| 货号 : | A390912 | |
| 分子式 : | C3H7NO2S | |
| 纯度 : | 97% | |
| 分子量 : | 121.16 | |
| MDL号 : | MFCD00064306 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,Room temperature In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
H2O: 30 mg/mL(247.61 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | L-Cysteine is a nutritionally semiessential amino acid and is present mainly in the form of L-cystine in the extracellular space. With the help of a transport system, extracellular L-cystine crosses the plasma membrane and is reduced to L-cysteine within cells by thioredoxin and reduced glutathione (GSH). Intracellular L-cysteine plays an important role in cellular homeostasis as a precursor for protein synthesis, and for production of GSH, hydrogen sulfide (H(2)S), and taurine[1]. L-Cysteine, an H2S donor, significantly alleviated brain injury after hypoxia-ischemic (HI) injury in neonatal mice. L-Cysteine attenuated the accumulation of CD11b+/CD45 high cells, activation of microglia and astrocytes and diminished HI-induced increases in reactive oxygen species and malondialdehyde within the lesioned cortex. In addition, L-Cysteine increased microtubule associated protein 1 light chain 3-II and Beclin1 expression, decreased p62 expression and phosphor-mammalian target of rapamycin and phosphor-signal transducer and activator of transcription 3[2]. In addition, overexpression of NCgl2566 and NCgl0580 resulted in enhanced L-cysteine production in an L-cysteine-producing recombinant strain of C. glutamicum[3]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
8.25mL 1.65mL 0.83mL |
41.27mL 8.25mL 4.13mL |
82.54mL 16.51mL 8.25mL |
| 参考文献 |
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