产品说明书

Protirelin

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Chemical Structure| 24305-27-9 同义名 : Thyrotropin-releasing-hormone;TRH;TSH-releasing Hormone;TRF;Thyrotropin-Releasing Factor;Thyroliberin;pGlu-His-Pro amide
CAS号 : 24305-27-9
货号 : A390641
分子式 : C16H22N6O4
纯度 : 98%
分子量 : 362.384
MDL号 : MFCD00038640
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(689.88 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00106119 Thyroid Diseases Phase 2 Completed - United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT01897844 Healthy Phase 1 Completed - Italy ... 展开 >> Centro Ricerche Cliniche Verona, Italy, 37134 收起 <<
NCT00106119 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.76mL

0.55mL

0.28mL

13.80mL

2.76mL

1.38mL

27.60mL

5.52mL

2.76mL
参考文献

[1]Van Sinay E, Mirabeau O, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4065-E4074.

[2]Noda Y, Tanaka M, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, protirelin) in the rat. Kurume Med J. 1979;26(2):107-12.