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Oleic acid

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Chemical Structure| 112-80-1 同义名 : (9Z)-9-十八烯酸 ;9-cis-Octadecenoic acid;9Z-Octadecenoic acid;D 100;C18:1 (cis-9) Fatty acid;Octadecenoic acid (cis-9);Elaidoic acid;9-Octadecenoic Acid;Oleate
CAS号 : 112-80-1
货号 : A387371
分子式 : C18H34O2
纯度 : 98%
分子量 : 282.461
MDL号 : MFCD00064242
存储条件:

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 60 mg/mL(212.42 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

无水乙醇: 100 mg/mL(354.03 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇

0.1 M NaOH: 100 mg/mL(354.03 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 Oleic acid is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is also used as an activator of Na+/K+ ATPase.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02646202 Gastroesophageal Varices Phase 3 Recruiting December 2021 Egypt ... 展开 >> Tropical medicine dept.-Tanta university hospital Recruiting Tanta, Egypt Contact: Sherief Abd-Elsalam       Sherif_tropical@yahoo.com 收起 <<
NCT02049034 Type 2 Diabetes Phase 4 Completed - United Kingdom ... 展开 >> University of Surrey FHMS Diabetes and Metabolic Medicine Guildford, Surrey, United Kingdom, GU2 7WG 收起 <<
NCT01931826 Schistosomiasis Mansoni ... 展开 >> Portal Hypertension Upper Gastrointestinal Bleeding 收起 << Not Applicable Completed - Brazil ... 展开 >> Universidade Federal de Alagoas Maceio, Alagoas, Brazil, 57000000 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.70mL

3.54mL

1.77mL

35.40mL

7.08mL

3.54mL

参考文献

[1]Liu Z, Xiao Y, et al. Effects of oleic acid on cell proliferation through an integrin-linked kinase signaling pathway in 786-O renal cell carcinoma cells. Oncol Lett. 2013 Apr;5(4):1395-1399.

[2]Harvey KA, Walker CL, et al. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. J Lipid Res. 2010 Dec;51(12):3470-80.