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Arjunolic acid

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Chemical Structure| 465-00-9 同义名 : -
CAS号 : 465-00-9
货号 : A386365
分子式 : C30H48O5
纯度 : 99+%
分子量 : 488.699
MDL号 : MFCD11113458
存储条件：

粉末

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(214.86 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Arjunolic acid, a natural peroxisome proliferator-activated receptor alpha agonist isolated and purified from the fruits of Terminalia chebula Retz., can protect against cisplatin-induced testicular injury by attenuating oxidative stress parameters along with downregulation of iNOS, TNF-α, and p38-MAPK testicular expressions.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.05mL

0.41mL

0.20mL

10.23mL

2.05mL

1.02mL

20.46mL

4.09mL

2.05mL
参考文献

[1]Bansal T, Chatterjee E, et al. Arjunolic acid, a peroxisome proliferator-activated receptor α agonist, regresses cardiac fibrosis by inhibiting non-canonical TGF-β signaling. J Biol Chem. 2017 Oct 6;292(40):16440-16462.

[2]Kalyanavenkataraman S, Nanjan P, et al. Discovery of arjunolic acid as a novel non-zinc binding carbonic anhydrase II inhibitor. Bioorg Chem. 2016 Jun;66:72-9.