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Prednisolone Acetate

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Chemical Structure| 52-21-1 同义名 : Prednisolone 21-acetate
CAS号 : 52-21-1
货号 : A386186
分子式 : C23H30O6
纯度 : 98%
分子量 : 402.481
MDL号 : MFCD00037710
存储条件:

粉末 Keep in dark place,Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(124.23 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:

2% DMSO+30% PEG 300+2% Tween 80+water 5 mg/mL

生物活性
描述 Prednisolone 21-acetate is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01685983 Prostate Cancer Phase 2 Completed - Korea, Republic of ... 展开 >> Busan, Korea, Republic of Cheongju-Si, Korea, Republic of Seongnam-Si, Gyeonggi-Do, Korea, Republic of Seoul, Korea, Republic of Taiwan Kaohsiung, Taiwan Taichung City, Taiwan Taichung, Taiwan Taipei, Taiwan Taoyuan County, Taiwan 收起 <<
NCT01685983 - Completed - -
NCT02002078 Esophageal Diseases Phase 4 Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.42mL

2.48mL

1.24mL

24.85mL

4.97mL

2.48mL

参考文献

[1]Garg P, Tuteja N, Qayum S. To Study the Efficacy of Difluprednate Ophthalmic Emulsion and Prednisolone Acetate Ophthalmic Suspension on Post-operative Inflammation in Cataract Surgery. J Clin Diagn Res. 2016 Dec;10(12):NC05-NC08.

[2]Jeng KW, Fine HF, et al. Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate. Retina. 2014 Oct;34(10):1990-6.