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Hydroxyhexamide

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Chemical Structure| 3168-01-2 同义名 : (±)-Hydroxyhexamid
CAS号 : 3168-01-2
货号 : A382168
分子式 : C15H22N2O4S
纯度 : 99%+
分子量 : 326.411
MDL号 : MFCD00871870
存储条件:

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 300 mg/mL(919.09 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.06mL

0.61mL

0.31mL

15.32mL

3.06mL

1.53mL

30.64mL

6.13mL

3.06mL

参考文献

[1]Asada S, Nagamine S, et al. Comparative pharmacokinetics of acetohexamide and its metabolite, hydroxyhexamide in laboratory animals. Chem Pharm Bull (Tokyo). 1989 Mar;37(3):760-5.

[2]Nagamine S, Nakae H, et al. [Interconversion model analysis for acetohexamide and its metabolite, hydroxyhexamide in the rat by application of the simultaneous multi-lines fitting technique] . Yakugaku Zasshi. 1988 Nov;108(11):1072-80.