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Acetyl-CoA Carboxylase-IN-1

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Chemical Structure| 179343-23-8 同义名 : -
CAS号 : 179343-23-8
货号 : A382107
分子式 : C13H9Br2N5
纯度 : 95%
分子量 : 395.052
MDL号 : MFCD12828288
存储条件：

粉末 Keep in dark place,Inert atmosphere,Room temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(88.6 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Acetyl-CoA Carboxylase-IN-1 serves as a potent inhibitor of acetyl-CoA carboxylase (ACC), displaying an IC50 value of less than 5 nM. Additionally, Acetyl-CoA Carboxylase-IN-1 exhibits antibacterial properties [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.53mL

0.51mL

0.25mL

12.66mL

2.53mL

1.27mL

25.31mL

5.06mL

2.53mL
参考文献

[1]Cifone MT, et, al. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. J Med Chem. 2022 Dec 22;65(24):16510-16525.