产品说明书

Lercanidipine

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Chemical Structure| 100427-26-7 同义名 : -
CAS号 : 100427-26-7
货号 : A381766
分子式 : C36H41N3O6
纯度 : 98%
分子量 : 611.727
MDL号 : MFCD00867978
存储条件：

粉末 Keep in dark place,Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(171.65 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
靶点

  • Calcium Channel
描述 Lercanidipine is a calcium channel blocker of the dihydropyridine class.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00424801 Microvascular Angina ... 展开 >> Hypertension 收起 << Not Applicable Terminated(Due to recent findi... 展开 >>ngs relating MRI contrast to nephrogenic systemic fibrosis) 收起 << December 2008 Denmark ... 展开 >> Aarhus Hospital Aarhus, Denmark, 8000 收起 <<
NCT00741585 Essential Hypertension ... 展开 >> Cardiovascular Disease Stroke Chronic Kidney Disease 收起 << Phase 4 Completed - Spain ... 展开 >> CS Friol Friol, Lugo, Spain, 27220 CS Baiona Baiona, Pontevedra, Spain, 36300 CS Bueu Bueu, Pontevedra, Spain, 36930 CS A Estrada La Estrada, Pontevedra, Spain, 26680 CS A Guarda La Guardia, Pontevedra, Spain, 36780 CS Valmiñor Nigran, Pontevedra, Spain, 36250 CS Panxón Nigrán, Pontevedra, Spain, 36340 CS Tomiño Tomiño, Pontevedra, Spain, 36200 Bioengineering & Chronobilogy Labs., University of Vigo Vigo, Pontevedra, Spain, 36200 Hospital do Meixoeiro Vigo, Pontevedra, Spain, 36200 CS Calle Cuba Vigo, Pontevedra, Spain, 36202 CS A Doblada Vigo, Pontevedra, Spain, 36205 CS Coia Vigo, Pontevedra, Spain, 36209 CS Sardoma Vigo, Pontevedra, Spain, 36214 CS Teis Vigo, Pontevedra, Spain, 36216 CS Vilaboa Vilaboa, Pontevedra, Spain, 36141 CS San Roque Vilagarcía De Arousa, Pontevedra, Spain, 36600 CS Fingoi Lugo, Spain, 27002 Complexo Hospitalario Universitario de Ourense Orense, Spain, 32005 CS Lerez Pontevedra, Spain, 36156 收起 <<
NCT02594410 Hypertension Phase 4 Completed - China ... 展开 >> Fuwai Hospital Beijing, China 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.63mL

0.33mL

0.16mL

8.17mL

1.63mL

0.82mL

16.35mL

3.27mL

1.63mL
参考文献

[1]Selvaraj N, Adhimoolam M, et al. Neuroprotective Effect of Lercanidipine- A Novel Calcium Channel Blocker in Albino Mice. J Clin Diagn Res. 2015 Nov;9(11):FF01-5.

[2]Cao TS, Huynh VM, et al. Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke. Curr Med Res Opin. 2015 Jan;31(1):163-70.