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Benzydamine HCl

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Chemical Structure| 132-69-4 同义名 : AF864;Benzydamine hydrochloride
CAS号 : 132-69-4
货号 : A374095
分子式 : C19H24ClN3O
纯度 : 98%
分子量 : 345.866
MDL号 : MFCD00078957
存储条件:

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 40 mg/mL(115.65 mM)

动物实验配方:
生物活性
描述 Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, antipyretic and local anesthetic activity.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01917942 Cancer of the Head and Neck Phase 3 Completed - New Zealand ... 展开 >> Auckland Hospital Auckland, New Zealand, 1001 收起 <<
NCT01432873 Mucositis Hem... 展开 >>atopoietic Stem Cell Transplantation 收起 << Phase 1 Phase 2 Unknown December 2012 Iran, Islamic Republic of ... 展开 >> Hematology-Oncology & SCT Research Center Recruiting Tehran, Iran, Islamic Republic of Contact: Molouk Hadjibabaie, Pharma D.    +989122838464       Principal Investigator: Molouk Hadjibabaie, Pharma D          Sub-Investigator: Zahra Jahangard rafsanjani, Pharma D 收起 <<
NCT03574246 Sore Throat N... 展开 >>ausea and Vomiting, Postoperative 收起 << Phase 4 Active, not recruiting November 30, 2018 Turkey ... 展开 >> Ankara University Faculty of Dentistry Ankara, Yenimahalle, Turkey, 06560 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.89mL

0.58mL

0.29mL

14.46mL

2.89mL

1.45mL

28.91mL

5.78mL

2.89mL

参考文献

[1]Hung NK, Wu CT, et al. Effect on postoperative sore throat of spraying the endotracheal tube cuff with benzydamine hydrochloride, 10% lidocaine, and 2% lidocaine. Anesth Analg. 2010 Oct;111(4):882-6.

[2]Epstein JB, Stevenson-Moore P, et al. Prevention of oral mucositis in radiation therapy: a controlled study with benzydamine hydrochloride rinse. Int J Radiat Oncol Biol Phys. 1989 Jun;16(6):1571-5.