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Ceftizoxime sodium

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Chemical Structure| 68401-82-1 同义名 : SKF-88373
CAS号 : 68401-82-1
货号 : A373119
分子式 : C16H16N5NaO8S
纯度 : 98%
分子量 : 461.382
MDL号 : MFCD01682036
存储条件：

粉末 Inert atmosphere,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 14 mg/mL(30.34 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(216.74 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Ceftizoxime Sodium is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT03098485 Microbiota An... 展开 >>ti-bacterial Agents 收起 << Not Applicable Active, not recruiting June 30, 2019 United States, Missouri ... 展开 >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 收起 <<
NCT00194532 Urinary Tract Infection Not Applicable Completed - United States, Florida ... 展开 >> University of Miami Miller School of Medicine Miami, Florida, United States, 33136 United States, Washington University of Washington Seattle, Washington, United States, 98195 收起 <<
NCT00194532 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.17mL

0.43mL

0.22mL

10.84mL

2.17mL

1.08mL

21.67mL

4.33mL

2.17mL
参考文献

[1]Turkeş C, Soyut H, et al. Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium. J Enzyme Inhib Med Chem. 2015;30(4):622-8.