生物活性 | |||
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靶点 |
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描述 | BQ-123, a strong and specific endothelin A (ETA) receptor blocker, boasts an IC50 of 7.3 nM and a Ki of 25 nM. It hinders endothelin-1-induced growth of human pulmonary artery smooth muscle cells and reduces blood pressure in various rat hypertension models[1][2][3]. | ||
作用机制 | BQ123 is a competitive antagonist selective for the ETA- receptor.[1] |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.64mL 0.33mL 0.16mL |
8.19mL 1.64mL 0.82mL |
16.37mL 3.27mL 1.64mL |
参考文献 |
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