7-Nitroindazole

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Chemical Structure| 2942-42-9 同义名 : -
CAS号 : 2942-42-9
货号 : A367353
分子式 : C7H5N3O2
纯度 : 98%
分子量 : 163.133
MDL号 : MFCD00022789
存储条件：

Pure form Keep in dark place,Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(643.64 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 7-Nitroindazole is a selective inhibitor of neuronal nitric oxide synthase (nNOS) and exhibits antinociceptive and cardiovascular effects. It serves as an important tool for studying the biological roles of nitric oxide in the central nervous system[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

6.13mL

1.23mL

0.61mL

30.65mL

6.13mL

3.06mL

61.30mL

12.26mL

6.13mL
参考文献

[1]Moore PK, et al. 7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure. Br J Pharmacol. 1993 Feb;108(2):296-7.

[2]Moore PK, et al. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol. 1993 Sep;110(1):219-24.