产品说明书

Coptisine

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Chemical Structure| 3486-66-6 同义名 : Coptisin
CAS号 : 3486-66-6
货号 : A365708
分子式 : C19H14NO4
纯度 : 99%+
分子量 : 320.319
MDL号 : MFCD03792689
存储条件：

粉末 Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Coptisine is a protoberberine isoquinoline alkaloid isolated and purified from the herbs of Chelidonium majus L., which can increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase .
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.12mL

0.62mL

0.31mL

15.61mL

3.12mL

1.56mL

31.22mL

6.24mL

3.12mL
参考文献

[1]Yu D, Tao BB, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.

[2]He K, Ye X, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015 Feb;50(2):185-94.