Glucosamine sulfate
产品说明书
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同义名 : | D-氨基葡萄糖硫酸盐 ;D-Glucosamine sulfate;D-Glucosamine sulphate;D-Glucosamine sulphate, Gevolox, Glucosamine sulfate, Glucosamine sulphate |
| CAS号 : | 29031-19-4 | |
| 货号 : | A364467 | |
| 分子式 : | C6H13NO5.H2SO4 | |
| 纯度 : | 98% | |
| 分子量 : | 277.25 | |
| MDL号 : | MFCD00135940 | |
| 存储条件： |
Pure form Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
H2O: 120 mg/mL(432.82 mM)，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | D-Glucosamine sulfate (Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. D-Glucosamine sulfate exhibits dose-dependent DPPH antioxidant activity[1]. Glucosamine sulfate's role in halting or reversing joint degeneration appears to be directly due to its ability to act as an essential substrate for, and to stimulate the biosynthesis of, the glycosaminoglycans and the hyaluronic acid backbone needed for the formation of the proteoglycans found in the structural matrix of joints[2]. Daily glucosamine-sulfate administration accelerates early phase of fracture repair in the rat tibia, with increased new bone formation and osteoblast lining histologically, but radiologic bone union is not favored on radiographs[3]. The Glucosamine Sulfate has a carryover effect like Disease modifying agents. Long-term treatment of Glucosamine Sulfate may reduce the dependence of NSAIDs (Non-Steroidal anti-inflammatory drugs) usage and delay the disease progression[4]. Glucosamine sulfate at the oral once-daily dosage of 1,500 mg is more effective than placebo in treating knee OA (knee osteoarthritis) symptoms[5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.61mL 0.72mL 0.36mL |
18.03mL 3.61mL 1.80mL |
36.07mL 7.21mL 3.61mL |
| 参考文献 |
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