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Imisopasem manganese

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Chemical Structure| 218791-21-0 同义名 : M40403;GC4403;SC72325;CG4419
CAS号 : 218791-21-0
货号 : A356744
分子式 : C21H31Cl2MnN5
纯度 : 99%
分子量 : 479.348
MDL号 : MFCD09954128
存储条件：

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 25 mg/mL(52.15 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxideMnSOD.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.43mL

2.09mL

1.04mL

20.86mL

4.17mL

2.09mL
参考文献

[1]Masini E, Cuzzocrea S, et al. Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo. Br J Pharmacol. 2002 Jul;136(6):905-17. Erratum in: Br J Pharmacol. 2002 Dec;137(8):1387.

[2]Salvemini D, Mazzon E, et al. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br J Pharmacol. 2001 Feb;132(4):815-27.