产品说明书
Yangambin
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同义名 : | - |
| CAS号 : | 13060-14-5 | |
| 货号 : | A356142 | |
| 分子式 : | C24H30O8 | |
| 纯度 : | 99+% | |
| 分子量 : | 446.49 | |
| MDL号 : | - | |
| 存储条件： |
粉末 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. Yangambin has central nervous system activity, presenting a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests, and hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.24mL 0.45mL 0.22mL |
11.20mL 2.24mL 1.12mL |
22.40mL 4.48mL 2.24mL |
| 参考文献 |
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