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Sulcotrione

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Chemical Structure| 99105-77-8 同义名 : -
CAS号 : 99105-77-8
货号 : A353475
分子式 : C14H13ClO5S
纯度 : 98%
分子量 : 328.768
MDL号 : MFCD01632349
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(319.37 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Sulcotrione, a β-triketene herbicide, inhibits HPPD. Sulcotrione is a time-dependent reversible inhibitor. Previously, similar results have been seen with natural β-triketone and synthetic β-triketone NTBC. However, this is the first time that such behaviour has been observed using purified HPPD and synthetic β-triketone, namely sulcotrione. Inhibition kinetics analyses using 3 hydroxyphenylpyruvate (HPP) and sulcotrione concentrations showed that Kmapp increased with increasing sulcotrione concentration. This behaviour is consistent with data in the literature describing Sulcotrione as a competitive inhibitor of HPPD[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.04mL

0.61mL

0.30mL

15.21mL

3.04mL

1.52mL

30.42mL

6.08mL

3.04mL

参考文献

[1]Rocaboy-Faquet E, et al. A novel amperometric biosensor for ß-triketone herbicides based on hydroxyphenylpyruvatedioxygenase inhibition: A case study for sulcotrione. Talanta. 2016;146:510-6.