Dimethomorph

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Chemical Structure| 110488-70-5 同义名 : -
CAS号 : 110488-70-5
货号 : A352219
分子式 : C21H22ClNO4
纯度 : 97%
分子量 : 387.857
MDL号 : MFCD01632781
存储条件:

Pure form Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 5 mg/mL(12.89 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Dimethomorph is classified as a fungicide within the group known as sterol biosynthesis inhibitors. It functions by inhibiting the formation of fungal cell walls. In addition, dimethomorph has been found to suppress androgen receptor (AR) activity in MDA-kb2 cells, demonstrating an IC20 value of 0.263 µM[1].[2].[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.58mL

0.52mL

0.26mL

12.89mL

2.58mL

1.29mL

25.78mL

5.16mL

2.58mL

参考文献

[1]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84(4):454-458.

[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.

[3]Yigal Cohen,, et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97(10):1274-83.