Burchellin

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Chemical Structure| 38276-59-4 同义名 : -
CAS号 : 38276-59-4
货号 : A343841
分子式 : C20H20O5
纯度 : 98+%
分子量 : 340.37
MDL号 : -
存储条件:

Pure form

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Burchellin, a natural product isolated and purified from the herbs of Ocotea cymbarum. with larvicidal activity, can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3) at concentrations ≥ 30 ppm, and has activity against Trypanosoma cruzi, by inducing trypomastigote death with IC(50)/24 h of 520 mM and 960 mM, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.94mL

0.59mL

0.29mL

14.69mL

2.94mL

1.47mL

29.38mL

5.88mL

2.94mL

参考文献

[1]Narciso JO, Soares RO, et al. Burchellin: study of bioactivity against Aedes aegypti. Parasit Vectors. 2014 Apr 8;7:172.

[2]Cabral MM, Barbosa-Filho JM, et al. Neolignans from plants in northeastern Brazil (Lauraceae) with activity against Trypanosoma cruzi. Exp Parasitol. 2010 Mar;124(3):319-24.