产品说明书
Hydroxy Itraconazole
 |
同义名 : | Itraconazole metabolite Hydroxy Itraconazole;R-63373;hydroxy-ITZ;OH-ITZ |
| CAS号 : | 112559-91-8 | |
| 货号 : | A343771 | |
| 分子式 : | C35H38Cl2N8O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 721.633 | |
| MDL号 : | MFCD28964104 | |
| 存储条件： |
粉末 Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 85 mg/mL(117.79 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Hydroxy itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02633709 | Spinal Muscular Atrophy | Phase 1 | Completed | - | Netherlands ... 展开 >> Pra International Group B.V Groningen, Netherlands, 9728 NZ 收起 << |
| NCT02093728 | Solid Tumours | Phase 1 | Completed | - | United States, Kansas ... 展开 >> Research Site Overland Park, Kansas, United States 收起 << |
| NCT02157883 | Advanced Non Small Cell Lung C... 展开 >>ancer Advanced (Inoperable) Non Small Cell Lung Cancer 收起 << | Phase 1 | Active, not recruiting | December 31, 2018 | United States, California ... 展开 >> Research Site San Diego, California, United States, 92123 United States, Ohio Research Site Cleveland, Ohio, United States, 44106-4950 Belgium Research Site Edegem, Belgium, 2650 Research Site Gent, Belgium, 9000 Korea, Republic of Research Site Seongnam-si, Korea, Republic of, 13620 Research Site Seoul, Korea, Republic of, 03080 Research Site Seoul, Korea, Republic of, 03722 Research Site Seoul, Korea, Republic of, 06351 Research Site Seoul, Korea, Republic of, 138-736 Netherlands Research Site Amsterdam, Netherlands, 1066 CX Research Site Maastricht, Netherlands, 6229 HX Research Site Rotterdam, Netherlands, 3015 CE Taiwan Research Site Taipei, Taiwan, 10002 Research Site Taipei, Taiwan, 11217 United Kingdom Research Site London, United Kingdom, SE1 9RT Research Site Manchester, United Kingdom, M20 4BX 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.39mL 0.28mL 0.14mL |
6.93mL 1.39mL 0.69mL |
13.86mL 2.77mL 1.39mL |
| 参考文献 |
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