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β-Amyrin acetate

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Chemical Structure| 1616-93-9 同义名 : -
CAS号 : 1616-93-9
货号 : A342890
分子式 : C32H52O2
纯度 : 98+%
分子量 : 468.754
MDL号 : MFCD00200955
存储条件:

粉末

液体 -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 beta-Amyrin acetrate, a natural cannabinoid receptor isolated and purified from the herbs of Alstonia boone, shows significant HMG-CoA-reductase and sEH inhibitory activities. beta-Amyrin acetate has cytotoxicity and a high antioxidant potential with an IC50 value of 158.2ug/mL, and could be a viable source of antioxidant and cytotoxic agents in cancer chemotherapy in the near future. It also has anti-inflammatory activity, with ID50 values in the range of 0.15-0.75 mM/ear, and exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.13mL

0.43mL

0.21mL

10.67mL

2.13mL

1.07mL

21.33mL

4.27mL

2.13mL

参考文献

[1]Askari VR, Fereydouni N, et al. β-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammation induced by lipopolysaccharide/interferon-γ and regulates Mφ1/Mφ2 balances. Biomed Pharmacother. 2018 Mar 1;101:438-446.

[2]Maurya R, Srivastava A, et al. β-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves. Phytomedicine. 2012 Jun 15;19(8-9):682-5.