Norgestimate metabolite Norelgestromin

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Chemical Structure| 53016-31-2 同义名 : Norgestimate metabolite;17-Deacetyl norgestimate;Norelgestromin, Norelgestromine, Levonorgestrel oxime, Norplant 3-oxime, D-Norgestrel 3-oxime;RWJ 10553;17-desacetyl Norgestimate;Levonorgestrel oxime;BRN 4202099;Norelgestromin;17-Deacylnorgestimate
CAS号 : 53016-31-2
货号 : A337544
分子式 : C21H29NO2
纯度 : 99%
分子量 : 327.461
MDL号 : MFCD03695603
存储条件:

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 18 mg/mL(54.97 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00983957 - Completed - -
NCT00983957 Chronic Hepatitis C Phase 1 Completed - United States, Arizona ... 展开 >> MDS Pharma Services (US), Inc Tempe, Arizona, United States, 85283 United States, Texas Covance Clinical Research Unit, Inc. Austin, Texas, United States, 78752 Canada, Quebec Local Institution St. Laurent, Quebec, Canada, H4R2N6 收起 <<
NCT02533427 HCV Infection Phase 1 Completed - New Zealand ... 展开 >> Christchurch, New Zealand 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.05mL

0.61mL

0.31mL

15.27mL

3.05mL

1.53mL

30.54mL

6.11mL

3.05mL

参考文献

[1]Abrams LS, Skee DM, et al. Pharmacokinetics of norelgestromin and ethinyl estradiol from two consecutive contraceptive patches. J Clin Pharmacol. 2001 Nov;41(11):1232-7.