产品说明书

Acesulfame potassium

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Chemical Structure| 55589-62-3 同义名 : 乙酰磺胺酸钾;乙酰舒泛钾;安塞蜜;乙酰舒泛钾,安塞蜜 ;Acesulfame (potassium salt);E950;Acesulfame potassium salt
CAS号 : 55589-62-3
货号 : A334842
分子式 : C4H4KNO4S
纯度 : 99%
分子量 : 201.242
MDL号 : MFCD00043833
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(248.46 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Acesulfame potassium constitutes an artificial sweetener. It has been observed that long-term exposure to Acesulfame potassium may influence cognitive functions, possibly through modifications in neuro-metabolic functions in mice[1].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00796354 Constipation Phase 3 Completed - Czech Republic ... 展开 >> Gastroenterologie s.r.o. Hradec Králové, Czech Republic, 500 02 EGK.s.r.o, Sanatorium sv. Anny Praha, Czech Republic, 130 00 Orlickoustecká Nemocnice a.s. Ústi Nad Orlicí, Czech Republic, 562 18 France Hôpital Hotel Dieu Clermont-Ferrand, France, 63058 Hôpital Archet II Nice, France, 06200 Hôpital Charles Nicolles Rouen, France, 76031 Germany Martin-Luther-Krankenhaus-Betriebs-GmbH Berlin, Germany, 14193 Gastroenterologische Gemeinschaftspraxis Münster, Germany, 48159 Facharztpraxis für Innere Medizin Wiesbaden, Germany, 65185 Italy Policlinico S. Orsola Malpighi Bologna, Italy, 40138 Università degli Studi di Genova Genova, Italy, 6 - 16132 Università degli Studi di Palermo Palermo, Italy, 129 - 90127 Università La Sapienza Roma, Italy, 00162 Poland Slaskie Centrum Osteoporozy Katowice, Poland, 40-084 Centrum Onkologii ul.Rentgena 5 Warsaw, Poland, 02-781 Prosen SMO Warszawa, Poland, 01-231 Katedra i Klinika Gastroenterologii i Hepatologii Wroclaw, Poland, 50-556 Sweden Sodra Alvsborgs Hospital (SAS) Borås, Sweden, SE-176-65 Karolinska University Hospital Solna Stockholm, Sweden, SE-171-76 United Kingdom St Marks Hospital Harrow, United Kingdom, HA1 3UJ John Radcliffe Hospital Oxford, United Kingdom, OX3 9DU 收起 <<
NCT03663231 Dry Mouth Not Applicable Recruiting September 15, 2019 United States, New York ... 展开 >> University of Rochester Eastman Dental Center Recruiting Rochester, New York, United States, 14620 Contact: Christine Lung, MS    585-275-5087    Christine_Lung@urmc.rochester.edu 收起 <<
NCT02890108 Insulin Sensitivity Not Applicable Unknown October 2016 Chile ... 展开 >> Institute of Nutrition and Tecnology of Food, University of Chile Recruiting Santiago, Metropolitan region, Chile Contact: Verónica Cornejo Espinoza, Director    +56229781 410    vcornejo@inta.uchile.cl    Contact: Sandra Hirsch Birn, Academic    +56229781495 ext +56229781499    shirsch@inta.uchile.cl    Principal Investigator: Romina A Goza Ferreira, Magister c          Principal Investigator: Sandra Hirsch Birn, Magister          Sub-Investigator: Gladys Barrera Acevedo, Magister 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.97mL

0.99mL

0.50mL

24.85mL

4.97mL

2.48mL

49.69mL

9.94mL

4.97mL

参考文献

[1]Cong WN, et al. Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PLoS One. 2013 Aug 7;8(8):e70257.