Desogestrel

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Chemical Structure| 54024-22-5 同义名 : Org-2969;Cerazette;Desogestrelum;Desogen
CAS号 : 54024-22-5
货号 : A332714
分子式 : C22H30O
纯度 : 98%
分子量 : 310.473
MDL号 : MFCD00869346
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 16 mg/mL(51.53 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00269620 Contraception Phase 4 Completed - United States, California ... 展开 >> UCLA-Harbor Los Angeles, California, United States United States, Illinois University of Chicago Chicago, Illinois, United States United States, Maryland Johns Hopkins Baltimore, Maryland, United States United States, Massachusetts Boston University Boston, Massachusetts, United States United States, New York Columbia University New York, New York, United States United States, Oregon Oregon Health Science University Portland, Oregon, United States United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States Magee-Womens Hospital Pittsburgh, Pennsylvania, United States, 15213 United States, Virginia Eastern Virginia Medical School Norfolk, Virginia, United States United States, Wisconsin University of Wisconsin Madison, Wisconsin, United States 收起 <<
NCT00042289 HIV Infections Phase 4 Recruiting September 30, 2019 -
NCT01903031 HIV-1 Infection Phase 2 Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.22mL

0.64mL

0.32mL

16.10mL

3.22mL

1.61mL

32.21mL

6.44mL

3.22mL
参考文献

[1]Gassen DT, Herter LD, et al. Evaluation of hormonal suppression with two contraceptive regimens using ethinyl estradiol and desogestrel. Arch Gynecol Obstet. 2013 Feb;287(2):289-94.

[2]Verhoeven CH, Krebbers SF, et al. In vitro and in vivo metabolism of desogestrel in several species. Drug Metab Dispos. 1998 Sep;26(9):927-36.