Scoparone

产品说明书

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Chemical Structure| 120-08-1 同义名 : Aesculetin dimethyl ether;6,7-Dimethylesculetin;Escoparone;6,7-Dimethoxycoumarin
CAS号 : 120-08-1
货号 : A332142
分子式 : C11H10O4
纯度 : 99%
分子量 : 206.195
MDL号 : MFCD00006871
存储条件：

Pure form Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(242.49 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Scoparone, a natural product isolated and purified from the herbs of Artemisia scoparia, with antifungal, antianginal, antioxidant, immunosuppression and vasorelaxation effects, protects against carbon tetrachloride-induced liver injury, is a very efficient inhibitor of ultraviolet radiation -induced lipid peroxidation and damage, and a phytoalexin associated with resistance of citrus to Phytophthora citrophthora.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.85mL

0.97mL

0.48mL

24.25mL

4.85mL

2.42mL

48.50mL

9.70mL

4.85mL
参考文献

[1]Park S, Kim JK, et al. Scoparone interferes with STAT3-induced proliferation of vascular smooth muscle cells. Exp Mol Med. 2015 Mar 6;47:e145.

[2]Lee SH, Jang HD. Scoparone attenuates RANKL-induced osteoclastic differentiation through controlling reactive oxygen species production and scavenging. Exp Cell Res. 2015 Feb 15;331(2):267-77.