Cepharanone B

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Chemical Structure| 53948-09-7 同义名 : Aristolactam BII
CAS号 : 53948-09-7
货号 : A326374
分子式 : C17H13NO3
纯度 : 98%
分子量 : 279.29
MDL号 : MFCD17214803
存储条件：

Pure form Sealed in dry,Room Temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Aristolactam BII, a natural product isolated and purified from the herbs of Aristolochia debilis Sieb. et Zucc, exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells by directly inhibiting the production of nitric oxide and shows significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.58mL

0.72mL

0.36mL

17.90mL

3.58mL

1.79mL

35.81mL

7.16mL

3.58mL
参考文献

[1]Nobsathian S, Tuchinda P, et al. A new conjugated amide-dimer from the aerial parts of Piper submultinerve. Nat Prod Res. 2012;26(19):1824-30.

[2]Kim SR, Sung SH, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6.