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Phenelzine sulfate

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Chemical Structure| 156-51-4 同义名 : 苯基乙基肼硫酸盐 ;Phenelzine (sulfate);W-1544A;NSC 170957
CAS号 : 156-51-4
货号 : A326367
分子式 : C8H14N2O4S
纯度 : 99%
分子量 : 234.273
MDL号 : MFCD00050687
存储条件:

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(448.2 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Phenelzine sulfate is a non-selective and irreversible monoamine oxidase inhibitor (MAOI), used as an antidepressant and anxiolytic.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01944657 1. Major Depressive Disorder Not Applicable Withdrawn(unable to enroll sub... 展开 >>jects) 收起 << December 2015 United States, Maryland ... 展开 >> Sheppard Pratt Health System Towson, Maryland, United States, 21204 收起 <<
NCT01253642 Hormone-Resistant Prostate Can... 展开 >>cer Metastatic Prostatic Adenocarcinoma Prostate Adenocarcinoma Recurrent Prostate Carcinoma 收起 << Phase 2 Terminated(low enrollment) - United States, Oregon ... 展开 >> OHSU Knight Cancer Institute Portland, Oregon, United States, 97239 United States, Washington Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109 Seattle Cancer Care Alliance Seattle, Washington, United States, 98109 收起 <<
NCT01253642 - Terminated(low enrollment) - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.27mL

0.85mL

0.43mL

21.34mL

4.27mL

2.13mL

42.69mL

8.54mL

4.27mL

参考文献

[1]Cebak JE, Singh IN, et al. Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by Scavenging the Reactive Carbonyls 4-Hydroxynonenal and Acrolein Leading to Cortical Histological Neuroprotection. J Neurotrauma. 2017 Apr 1;34(7):1302-1317.