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2'-Deoxycytidine hydrochloride

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Chemical Structure| 3992-42-5 同义名 : 2'-Deoxycytidine monohydrochloride;Deoxycytidine hydrochloride;dC;2'-Deoxycytidine (hydrochloride);NSC 83251
CAS号 : 3992-42-5
货号 : A322509
分子式 : C9H14ClN3O4
纯度 : 98%
分子量 : 263.678
MDL号 : MFCD00012840
存储条件:

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 25 mg/mL(94.81 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 40 mg/mL(151.7 mM)

动物实验配方:
生物活性
描述 2'-Deoxyguanosine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.79mL

0.76mL

0.38mL

18.96mL

3.79mL

1.90mL

37.93mL

7.59mL

3.79mL

参考文献

[1]Hole EO, Sagstuen E, et al. Free radical formation in X-irradiated crystals of 2'-deoxycytidine hydrochloride. Electron magnetic resonance studies at 10 K. Radiat Res. 2000 Jun;153(6):823-34.

[2]Buchman VM, Belyanchikova NI, et al. 2'-Deoxycytidine hydrochloride protection of mice against the lethal toxicity of cytosine arabinoside. Absence of protection of bone marrow lymphocytes. Cancer Chemother Pharmacol. 1979;3(4):229-34.