Theanine

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Chemical Structure| 3081-61-6 同义名 : 左旋茶氨酸 ;L-Glutamic Acid γ-ethyl amide;Nγ-Ethyl-L-glutamine;Theanine;NSC 21308;5-N-ethyl-Glutamine;γ-ethylamino-L-Glutamic Acid
CAS号 : 3081-61-6
货号 : A320722
分子式 : C7H14N2O3
纯度 : 98%
分子量 : 174.198
MDL号 : -
存储条件：

Pure form Keep in dark place,Inert atmosphere,Room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 150 mg/mL(861.09 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 L-Theanine is an amino acid ingredient in green tea with a structural analogy to L-glutamine. L-Theanine accumulation consisted of at least two different components with Km values of 42.3 µM and 1.88 mM, and Vmax values of 3.92 and 104.2 nmol/h/mg protein, respectively. L-Theanine efficiently suppressed elevations of systemic blood pressure and brain 5-hydroxyindoles levels in spontaneous hypertensive rats.A prior intracerebroventricular injection of L-Theanine protected the hippocampal CA1 pyramidal neurons against delayed neuronal cell death in gerbils with bilateral forebrain global ischemia[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.74mL

1.15mL

0.57mL

28.70mL

5.74mL

2.87mL

57.41mL

11.48mL

5.74mL
参考文献

[1]Perez-Vargas JE, Zarco N, et al. l-Theanine prevents carbon tetrachloride-induced liver fibrosis via inhibition of nuclear factor κB and down-regulation of transforming growth factor β and connective tissue growth factor. Hum Exp Toxicol. 2016 Feb;35(2):135-46.

[2]Mu W, Zhang T, Jiang B. An overview of biological production of L-theanine. Biotechnol Adv. 2015 May-Aug;33(3-4):335-42.

[3]Yoneda Y. An L-Glutamine Transporter Isoform for Neurogenesis Facilitated by L-Theanine. Neurochem Res. 2017 Oct;42(10):2686-2697. doi: 10.1007/s11064-017-2317-6. Epub 2017 Jun 9. PMID: 28597057.