产品说明书

Thonzylamine

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Chemical Structure| 91-85-0 同义名 : Neohetramine
CAS号 : 91-85-0
货号 : A319179
分子式 : C16H22N4O
纯度 : 95%
分子量 : 286.372
MDL号 : MFCD00865672
存储条件：

粉末 Inert atmosphere,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(366.66 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Thonzylamine is an orally active H1 histamine receptor antagonist, demonstrates strong antihistaminic and antianaphylactic effects. It is utilized in research related to hypersensitivity diseases, nasal congestion, allergic conjunctivitis, and other allergic conditions[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.49mL

0.70mL

0.35mL

17.46mL

3.49mL

1.75mL

34.92mL

6.98mL

3.49mL
参考文献

[1]Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27(24): 115127.

[2]AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59(5): 438-41.