产品说明书

Arglabin

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Chemical Structure| 84692-91-1 同义名 : (+)-Arglabin
CAS号 : 84692-91-1
货号 : A318056
分子式 : C15H18O3
纯度 : 98%
分子量 : 246.302
MDL号 : MFCD11519463
存储条件:

粉末 Keep in dark place,Sealed in dry,Store in freezer, under -20°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(426.31 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, which is a NLRP3 inflammasome inhibitorand exhibits anti-inflammatory and antitumor activities[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.06mL

0.81mL

0.41mL

20.30mL

4.06mL

2.03mL

40.60mL

8.12mL

4.06mL

参考文献

[1]Abderrazak A, et al. Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet. Circulation. 2015;131(12):1061-1070.

[2]Lone SH, et al. Arglabin: From isolation to antitumor evaluation. Chem Biol Interact. 2015;240:180-198.