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Eprobemide

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Chemical Structure| 87940-60-1 同义名 : LIS 630;Befol
CAS号 : 87940-60-1
货号 : A312096
分子式 : C14H19ClN2O2
纯度 : 99%+
分子量 : 282.766
MDL号 : MFCD00495881
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(424.38 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Eprobemide, employed as an antidepressant, is a non-competitive reversible inhibitor of monoamine oxidase A, selectively targeting serotonin deamination[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.68mL

3.54mL

1.77mL

35.36mL

7.07mL

3.54mL
参考文献

[1]Gol'dina OA, et al. The action of befol and its derivatives on monoamine oxidase of different origins. Biull Eksp Biol Med. 1991 Mar;111(3):279-80.

[2]Donskaya, et al. Antidepressant Befol Synthesized Via Interaction of 4-Chloro-N-(3-chloropropyl)benzamide with Morpholine. Pharmaceutical Chemistry Journal, 2004 Jun; 38(7): 381-384.