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β-Amyrin

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Chemical Structure| 559-70-6 同义名 : β-香树素 ;NSC 527971;Olean-12-en-3β-ol;beta-Amyrin, β-amyrin, beta-Amyrenol, Amyrin,;(+)-β-Amyrin
CAS号 : 559-70-6
货号 : A295356
分子式 : C30H50O
纯度 : 98+%
分子量 : 426.72
MDL号 : MFCD00017381
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMF: 10 mg/mL(23.43 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 beta-Amyrin, a natural cannabinoid receptors agonist isolated and purified from the stem bark of Alstonia boonei, has anti-inflammatory activity. Beta-Amyrin significantly inhibits PGE2, IL-6 secretion, and NF-κB activation in a concentration-dependent manner on LPS-induced hPBMCs.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.34mL

0.47mL

0.23mL

11.72mL

2.34mL

1.17mL

23.43mL

4.69mL

2.34mL
参考文献

[1]Askari VR, Fereydouni N, et al. β-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammation induced by lipopolysaccharide/interferon-γ and regulates Mφ1/Mφ2 balances. Biomed Pharmacother. 2018 Mar 1;101:438-446.

[2]Okoye NN, Ajaghaku DL, et al. beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity. Pharm Biol. 2014 Nov;52(11):1478-86.