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Senkyunolide H

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Chemical Structure| 94596-27-7 同义名 : -
CAS号 : 94596-27-7
货号 : A295128
分子式 : C12H16O4
纯度 : 98%
分子量 : 224.253
MDL号 : MFCD32182625
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(468.22 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Senkyunolide H, a natural prototype for an anti-atherosclerotic drug isolated and purified from the roots of Ligusticum chuanxiong hort, can reduce the metamorphose damage of the RBC caused by ConA, and alleviated the aggregation of the RBC.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.46mL

0.89mL

0.45mL

22.30mL

4.46mL

2.23mL

44.59mL

8.92mL

4.46mL
参考文献

[1]Xiong YK, Liang S, et al. [Preparation of ferulic acid, senkyunolide I and senkyunolide H from Ligusticum chuanxiong by preparative HPLC] . Zhongguo Zhong Yao Za Zhi. 2013 Jun;38(12):1947-50. Chinese.

[2]Zhao X, Ma T, et al. Simultaneous determination of senkyunolide I and senkyunolide H in rat plasma by LC-MS: application to a comparative pharmacokinetic study in normal and migrainous rats after oral administration of Chuanxiong Rhizoma extract. Biomed Chromatogr. 2015 Sep;29(9):1297-303.