产品说明书

Ethopabate

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Chemical Structure| 59-06-3 同义名 : 2-乙氧-4-乙酰胺苯甲酯 ;Ethyl pabate
CAS号 : 59-06-3
货号 : A294987
分子式 : C12H15NO4
纯度 : 99%
分子量 : 237.252
MDL号 : MFCD00075809
存储条件:

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 50 mg/mL(210.75 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Ethopabate is an antiprotozoal agent which has been widely used to treat and prevent coccidiosis in chickens[1]. Treatment with toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate prevented mortality in chickens infected with field isolates of Eimeria tenella. Amprolium/ethopabate was the most effective drug in reducing lesions caused by the parasites[2]. Average recoveries from poultry samples fortified with 10, 15, and 20 microg/kg levels of ethopabate were 100-105%[3]. Recoveries of ethopabate added to chicken tissues at levels of 0.01 and 0.05 ppm were 87.8 and 92.7%, respectively. The detection limit was 100 pg for ethopabate standard, and 0.5 ppb in chicken tissues[4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.21mL

0.84mL

0.42mL

21.07mL

4.21mL

2.11mL

42.15mL

8.43mL

4.21mL

参考文献

[1]Nasr JJ, Shalan S. Spectrofluorimetric analysis of ethopabate in veterinary formulations with application to residue determination in chicken muscles and liver. Luminescence. 2014;29(8):1188‐1193

[2]Chapman HD. Chemotherapy of caecal coccidiosis: efficacy of toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate, given in drinking water, against field isolates of Eimeria tenella. Res Vet Sci. 1989;46(3):419‐420

[3]Granja RH, Niño AM, Zucchetti RA, Niño RE, Salerno AG. Validation of a high-performance liquid chromatographic method with UV detection for the determination of ethopabate residues in poultry liver. J AOAC Int. 2008;91(6):1483‐1487

[4]Nagata T, Saeki M, Nakazawa H, Fujita M, Takabatake E. Sensitive determination of ethopabate residues in chicken tissues by liquid chromatography with fluorometric detection. J Assoc Off Anal Chem. 1985;68(1):27‐28